Abstract: The basis of traditional chinese medicine depends on the concept of time and its rythms. The terrestrial branches ('Di Zhi') and the celestial trunks ('Tian Gan'), at the beginning of the sexagesimal cycle allow the possibility of explaining great energy movements, of conceiving a system of meterorological forecasting and of predicting the emergence of an eventual chronopathology. Following a definition of the biological rythms according to western ideas, and then a bibliographic study of circadian and circannual chronopathology, the author carries out a study of the union of the 'Tian Gan' and the 'Di Zhi' with the object of establishing a protocol of an effective means for detecting climatological and chronopathological changes taking place during the sexagesimal cycle.

The third chapter, dealing with a comparison 01 the climates of China and France, to a certain extent gives an idea of understanding the conditions for making use choronopathology such as it derives from the neil jing su wen, wich is the subject of the fourth chapter.
the aim of chapters 5, 6 and 7 is, first of all, to show how to calculate climatological description of the years from 1987 to 1992, according to chinese data, and finally come the correlations between the chinese predictions and the meteorological records provided by Meteo France.

 An epidemiological study of the type case-witness relative to 7, 342 medical operations has subsequently established the link between the seasons and western chronopathology. Next the author carried out a study to find the links between these data and the knowledge coming from traditional chinese medicine. An examination was made of the association between humidity and rain tall 50 as to discover the source of rheumatic pains connected with 'stationary bi'. To bring this work to a close, the author established the exactitude of Chinese observations, which since the dawn of time has linked the the 'awood of the springtime' to the liver with its allergies, by the discovery, using the cosinor method, of the circannual rhythm of the allergy syndromes with a springtime acrophase.

Keywords : chrono-acupuncture, terrestrial branches, 'Di Zhi', celestial trunks, 'Tian Gan', biological rythms, chronopathology, epidemiology, meteorological predictions, seasons, humidity, climatology, rhumatology, allergy, cosinor.

French abstract